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US biotech billionaire Patrick Soon-Shiong on Wednesday opened a plant in Cape Town that will be the first in Africa to produce Covid-19 vaccines from start to finish.

French star Gaspard Ulliel, who played a young Hannibal Lecter and had a top role in a new Marvel TV series, died on Wednesday at 37 following a skiing accident, his family said.

Dozens of firefighters rallied in Tehran to protest their living conditions, local media reported on Wednesday, marking the fifth anniversary of a tower blaze that caused the death of many of their colleagues.

Queen Elizabeth II's second son Prince Andrew has deactivated his social media accounts, users said Wednesday, as he faces a US civil case for sexual assault.

Expanding nature preserves will not be enough to stem a rising tide of extinctions, a panel of experts warned Wednesday, taking aim at a draft treaty tasked with rescuing Earth's animal and plant life.

Former Newcastle and France midfielder Hatem Ben Arfa signed for reigning French champions Lille until the end of the season on Wednesday, the club said.

Procter & Gamble raised its full-year forecast Wednesday as robust consumer demand enabled the company to notch higher sales even as it increased prices on consumer goods.

Indian former doubles world number one Sania Mirza said Wednesday she will retire from tennis at the end of this season with injuries taking their toll.

German prosecutors accused a Syrian doctor Wednesday of torturing detainees and killing one of them while working in military hospitals in his war-torn homeland, on the first day of a landmark crimes against humanity trial in Frankfurt.

Beijing on Wednesday reported five new locally transmitted coronavirus cases, raising fears of a fresh outbreak less than three weeks before the city hosts the Winter Olympics.

Russian soldiers completed their draw down from Kazakhstan, the defence ministry said Wednesday, as the Central Asian country lifted a state of emergency imposed after unprecedented unrest and signs of a power struggle.

Four-time Grand Slam champion Naomi Osaka said Wednesday that she is taking inspiration at the Australian Open from none other than Nick Kyrgios.

Time was running out for Pudding.

Naomi Osaka played the role of smiling assassin and top seed Ashleigh Barty was ruthlessly efficient at the Australian Open on Wednesday as they moved closer to a potential fourth-round showdown.

The Berlinale, Europe's first major film festival of the year, will take place next month as an in-person event, organisers confirmed Wednesday, just as the Omicron wave is expected to peak in Germany.

Naomi Osaka said she drew on past experience in a composed beating of Madison Brengle on Wednesday to move closer to a blockbuster Australian Open clash with top seed Ashleigh Barty.

Anders Behring Breivik, who is seeking conditional release just 10 years after carrying out Norway's deadliest peacetime attack, poses the same danger to society as a decade ago, a psychiatrist said in court Wednesday.

Rising American star Sebastian Korda battled to his first career five-set win to stay alive at the Australian Open on Wednesday -- then spoke of taking inspiration from his Grand Slam-winning father.

More than 100 millionaires made an unusual plea on Wednesday: "Tax us now".

A Belgian court sentenced a Vietnamese man to 15 years in prison on Wednesday after convicting him of being the ringleader in the trafficking of 39 migrants found dead in a lorry.

Israel's justice minister on Wednesday pledged a full investigation into allegations that the controversial Pegasus spyware was used on Israeli citizens, including people who led protests against former premier Benjamin Netanyahu.

Boris Johnson has long had a socially distanced relationship with the truth, but the UK prime minister's devil-may-care insouciance was pivotal to his Conservative party's staggering election win in 2019.

Emma Raducanu will reach the top level of women's tennis but first must absorb the lessons from her dizzying rise, says the director of a charity that helped fund her eye-catching journey.

Qatar World Cup ticket sales were launched at reduced prices on Wednesday with residents and migrant workers able to attend games for just $11 as concerns persist over Covid-19.

A Taliban fighter has been arrested for shooting dead a Hazara woman at a checkpoint in the Afghan capital as she returned from a wedding, a spokesman for the group said Wednesday.

Rafael Nadal rumbled into the third round of the Australian Open on Wednesday and warned that the best was yet to come after a troubled year with injury.

Japan's government approved new coronavirus restrictions on a large part of the country, including Tokyo, on Wednesday as it battles record infections fuelled by the Omicron variant.

English golfer Paul Casey on Wednesday defended Saudi Arabia's $200 million cash injection to revive the Asian Tour, following criticism of the deal over the oil-rich kingdom's human rights record.

Hong Kong's government faced outrage Wednesday over its decision to cull thousands of small animals after hamsters in a pet store tested positive for Covid-19.

The Taliban's prime minister called Wednesday on Muslim nations to be the first to officially recognise their government, as aid-dependent Afghanistan faces economic collapse.

Robert Tomlinson picks rhubarb stalks by candlelight in the dark, carrying on a century-old family tradition that survives today despite the challenges posed to his business by Brexit and climate change.

Taiwan said Wednesday its deputy leader will go to the inauguration of Honduran president-elect Xiomara Castro as the island faces the potential loss of yet another diplomatic ally in Latin America.